Scientist II Protein Biology

About the job

About The Company

Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science with annual revenue of approximately $44 billion. Our Mission is to enable our customers to make the world healthier cleaner and safer. Whether our customers are accelerating life sciences research solving analytical challenges growing efficiency in their laboratories improving patient health through diagnostics or developing and manufacturing lifechanging therapies we are here to support them. Our distributed team delivers an outstanding combination of innovative technologies purchasing convenience and pharmaceutical services through our industryleading brands including Thermo Scientific Applied Biosystems Invitrogen Fisher Scientific Unity Lab Services Patheon and PPD. Our Innovative Laboratory technologies Services makes it easier for customers.

About Team: Antibody team

The antibody team is involved in engineering and development of antibodies with a deep focus on reagent quality and specificity. The core activities of team include design development purification conjugation and testing of antibodies in a variety of immunoassay applications using groundbreaking tools and technologies. The goal of the program is advanced product development and creation of product specific information to promote research use.

Role Responsibilities

To be an integral part of an antibody development team with a focus on performance and specificity using innovative molecular protein and cell biology methods.

Responsibilities:

Contribute in a fast paced environment towards Antibody development Validation

Project leadership role in new antibody development programs with vast experience in experimental planning and execution to meet the program objectives.

Design and experimental execution interpreting data and data presentation to the stakeholders.

Drive ideation within teams to enable development of successful protocols for effective transfer to operation teams.

Serve as domain expert in the field of protein biology to provide inputs and guidance towards driving innovation and cross team collaborations.

Knowledge of product commercialization processes from concept to launch including early feasibility development and validation phases.

Support manufacturing team for technical support and quality by providing technical guidance.

Candidate Requirement:

Education Experience levels:

Applicants should have Masters with greater than 5 years relevant experience or PhD with greater than 2 years experience in a life sciences field with a strong focus on structural biology protein design protein purification molecular biology immunology biotechnology or biochemistry.

Nature of experience:

Extensive experience and familiarity with antibody or protein engineering rational design and molecular biology using tools and methodologies of structural biology and protein modeling and visualization tools such as Pymol Shrodinger Discovery Studio or other such programs.

Experience in the field of molecular biology protein expression protein purification and proteinprotein interaction protein structure function relationships and immunogen designs.

Expertise in development of conjugation chemistries or performing antibody conjugations is desired

Proficient in molecular biology workflows such as highthroughput molecular cloning plasmid vector construction PCRs Restriction digestion Ligation Transformation Mini and maxi preps sequencing

Thorough in biochemical and immunoassay workflows such as recombinant protein expression and purification ELISA SDSPAGE Western blotting IF IHC

Ability to provide technical trouble shooting to resolve scientific problems.

Proficient in software or platforms for molecular biology and sequence analysis MS Office and statistical software such as GraphPad Prism.

Authorship of peerreviewed publications with postdoctoral experience and a strong independent understanding of standard and emerging research protocols and techniques are preferred. GLP experience is a must.

Prior project leadership experience preferred.

The successful candidate will be selfmotivated and a selfstarter who is excellent at learning and applying new concepts for process or product improvements possess excellent oral and written communication skills to connect to peers and leadership and will be an excellent teammate with the ability to work with diverse colleagues.

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Remote Work :

No